Recombinant Human CDC14A Protein, His&GST-tagged

• Cat.No.: CDC14A-713H
• Product Overview: Recombinant Human CDC14A Protein (Met1-Lys199) with His&GST tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 53.1 kDa; Accurate Molecular Mass: 53 kDa
• Protein length: Met1-Lys199
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CDC14A CDC14 cell division cycle 14 homolog A (S. cerevisiae) [ Homo sapiens (human) ]
• Official Symbol: CDC14A
• Synonyms: CDC14A; CDC14 cell division cycle 14 homolog A (S. cerevisiae); CDC10 (cell division cycle 10, S. cerevisiae, homolog); dual specificity protein phosphatase CDC14A; cdc14; Cdc14A1; Cdc14A2; hCDC14
• Gene ID: 8556
• mRNA Refseq: NM_003672
• Protein Refseq: NP_003663
• MIM: 603504
• UniProt ID: Q9UNH5