Recombinant Human CD82

Description :	This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Protein length :	267 amino acids
Molecular Weight :	55.110kDa inclusive of tags
Source :	Wheat germ
Tissue specificity :	Lymphoid specific.
Form :	Liquid
Purity :	Proprietary Purification
Storage buffer :	pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids :	MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSS FISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNE VRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTD NAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRT QSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI VELLGMVLSICLCRHVHSEDYSKVPKY
Sequence Similarities :	Belongs to the tetraspanin (TM4SF) family.
Tag :	Non

Gene Name	CD82 CD82 molecule [ Homo sapiens ]
Official Symbol	CD82
Synonyms	CD82; CD82 molecule; CD82 antigen , KAI1, kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and IA4)) , ST6; CD82 antigen; IA4; R2; R2 leukocyte antigen; suppression of tumorigenicit
Gene ID	3732
mRNA Refseq	NM_001024844
Protein Refseq	NP_001020015
MIM	600623
Uniprot ID	P27701
Chromosome Location	11p11.2
Pathway	Direct p53 effectors, organism-specific biosystem; p53 signaling pathway, organism-specific biosystem; p53 signaling pathway, conserved biosystem;
Function	protein binding;