Recombinant Human CD1D Protein, Fc-tagged

• Cat.No.: CD1D-828H
• Product Overview: Recombinant Human CD1D(Glu20-Ser301), transcript variant 1, fused with Fc tag at C-terminal was expressed in HEK295 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 20-301 a.a.
• Description: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.
• Form: 1 x PBS, pH7.4, 10% glycerol.
• Molecular Mass: 59 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CD1D CD1d molecule [ Homo sapiens ]
• Official Symbol: CD1D
• Synonyms: CD1D; CD1d molecule; CD1d antigen , CD1D antigen, d polypeptide; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; R3; CD1A; MGC34622
• Gene ID: 912
• mRNA Refseq: NM_001766
• Protein Refseq: NP_001757
• MIM: 188410
• UniProt ID: P15813