Recombinant Human CCNDBP1 Protein, His-tagged

• Cat.No.: CCNDBP1-2994H
• Product Overview: Recombinant Human CCNDBP1 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg. Store at -80 Centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 40.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CCNDBP1 cyclin D-type binding-protein 1 [ Homo sapiens ]
• Official Symbol: CCNDBP1
• Synonyms: DIP1; GCIP; HHM
• Gene ID: 23582
• mRNA Refseq: NM_012142
• Protein Refseq: NP_036274
• MIM: 607089
• UniProt ID: O95273