CCNDBP1
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Official Full Name
cyclin D-type binding-protein 1 -
Overview
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009] -
Synonyms
CCNDBP1;cyclin D-type binding-protein 1;HHM;DIP1;GCIP;cyclin-D1-binding protein 1;human homolog of Maid;D-type cyclin-interacting protein 1;grap2 and cyclin-D-interacting protein
Recombinant Proteins
- Human
- Rat
- Mouse
- Cynomolgus
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- E.coli
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
CCNDBP1 involved in several pathways and played different roles in them. We selected most pathways CCNDBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNDBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CCNDBP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNDBP1 itself. We selected most functions CCNDBP1 had, and list some proteins which have the same functions with CCNDBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JDP2,PBXIP1,SIL1,BMX,C4orf46,FZD8,NFKB2,CENPL,MUC2,SNX10 |
Interacting Protein
CCNDBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNDBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNDBP1.
IMP3;PIAS2;PSMB10;RPL28;ZNF136
Resources
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References
- Guo, J; Yang, LX; et al. Knocking down the expression of SYF2 inhibits the proliferation of glioma cells. MEDICAL ONCOLOGY 31:-(2014).
- Denes, D; Edit, A; et al. Cell-cycle control as a target for calcium, hormonal and developmental signals: the role of phosphorylation in the retinoblastoma-centred pathway. ANNALS OF BOTANY 107:1193-1202(2011).
