Recombinant Human CCDC134, GST-tagged

Cat.No. : CCDC134-10789H
Product Overview : Recombinant Human CCDC134 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability March 15, 2025
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Species : Human
Source : E.coli
Tag : GST
Protein Length : 1-229a.a.
Description : This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name CCDC134 coiled-coil domain containing 134 [ Homo sapiens ]
Official Symbol CCDC134
Synonyms CC134_HUMAN; ccdc134; coiled-coil domain containing 134; Coiled-coil domain-containing protein 134; dJ821D11.3; FLJ22349; MGC21013; CCDC134
Gene ID 79879
mRNA Refseq NM_024821.2
Protein Refseq NP_079097.1
UniProt ID Q9H6E4
Chromosome Location 22q13.2

Not For Human Consumption!

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