Recombinant Human CCDC115, His-tagged

• Cat.No.: CCDC115-10785H
• Product Overview: Recombinant Human CCDC115 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-180a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CCDC115 coiled-coil domain containing 115 [ Homo sapiens ]
• Official Symbol: CCDC115
• Synonyms: CCDC115; coiled-coil domain containing 115; coiled-coil domain-containing protein 115; ccp1; FLJ30131; MGC12981
• Gene ID: 84317
• mRNA Refseq: NM_032357
• Protein Refseq: NP_115733
• MIM: 613734
• UniProt ID: Q96NT0
• Chromosome Location: 2q21.1