Recombinant Human CBX1 Protein, DDK-tagged

• Cat.No.: CBX1-2721H
• Product Overview: Recombinant Human CBX1 protein, fused to DDK-tagged at C-terminus, was expressed in Insect cells.

Specification

• Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: Insect cells
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10% glycerol
• Molecular Mass: 21.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CBX1 chromobox homolog 1 [ Homo sapiens ]
• Official Symbol: CBX1
• Synonyms: CBX; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta
• Gene ID: 10951
• mRNA Refseq: NM_001127228
• Protein Refseq: NP_001120700
• MIM: 604511
• UniProt ID: P83916