Recombinant Human Cathepsin H, T7-tagged

• Cat.No.: CTSH-3042H
• Product Overview: Recombinant Human CTSH was produced inE.coliwith a T7 tag at N-terminus. MW = 37378 Da (23-335 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 23-335 a.a.
• Description: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: CTSH cathepsin H [ Homo sapiens ]
• Synonyms: CTSH; cathepsin H; CPSB; ACC-4; ACC-5; MGC1519; minichain; DKFZp686B24257; cathepsin H; aleurain; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; EC 3.4.22.16; Cathepsin H mini chain; Cathepsin H heavy chain; Cathepsin H light chain
• Gene ID: 1512
• mRNA Refseq: NM_004390
• Protein Refseq: NP_004381
• MIM: 116820
• UniProt ID: P09668
• Chromosome Location: 15q25.1
• Pathway: Lysosome
• Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; kininogen binding; peptidase activity; protein binding; protein complex binding