Recombinant Human CAPSL, GST-tagged

• Cat.No.: CAPSL-10713H
• Product Overview: Recombinant Human CAPSL protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-198a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CAPSL calcyphosine-like [ Homo sapiens ]
• Official Symbol: CAPSL
• Synonyms: CAPSL; calcyphosine-like; calcyphosin-like protein; MGC26610
• Gene ID: 133690
• mRNA Refseq: NM_001042625
• Protein Refseq: NP_001036090
• UniProt ID: Q8WWF8
• Chromosome Location: 5p13.2
• Function: calcium ion binding