Recombinant Human CAPN3 protein

• Cat.No.: CAPN3-31H
• Product Overview: Recombinant Human CAPN3, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 156aa
• Description: Phosphatidylethanolamine-binding protein 1 binds ATP, opioids and phosphatidylethanolamine. It has lower affinity for phosphatidylinositol and phosphatidylcholine. It is thought that this protein also function as serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PEBP-1 also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. It seems to be mediated by a specific receptor.
• Form: 20mM Tris.Cl, 50mM NaCl, 20% Glycerol, pH9.0.
• Molecular Mass: 18.2kDa
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80°C and avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: CAPN3 calpain 3, (p94) [ Homo sapiens ]
• Official Symbol: CAPN3
• Synonyms: CAPN3; LGMD2, LGMD2A; calpain-3; CANP3; nCL 1; p94; calpain L3; LGMD2; nCL-1; CANPL3; LGMD2A; MGC4403; MGC10767; MGC11121; MGC14344
• Gene ID: 825
• mRNA Refseq: NM_000070
• Protein Refseq: NP_000061
• MIM: 114240
• UniProt ID: P20807
• Chromosome Location: Integrin-mediated cell adhesion, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Pathway: calcium ion binding; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity; catalytic activity; cysteine-type peptidase activity