Recombinant Human C12orf65 Protein, MYC/DDK-tagged

• Cat.No.: C12orf65-624H
• Product Overview: Recombinant Human C12orf65, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 18.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: C12orf65 chromosome 12 open reading frame 65 [ Homo sapiens (human) ]
• Official Symbol: C12orf65
• Synonyms: C12orf65; chromosome 12 open reading frame 65; CL065_HUMAN; COXPD7; mitochondrial; Probable peptide chain release factor C12orf65; probable peptide chain release factor C12orf65, mitochondrial; SPG55
• Gene ID: 91574
• mRNA Refseq: NM_152269
• Protein Refseq: NP_689482
• MIM: 613541
• UniProt ID: Q9H3J6