Recombinant Human C12orf65, GST-tagged

• Cat.No.: C12orf65-10376H
• Product Overview: Recombinant Human C12orf65 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 11-94a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: C12orf65 chromosome 12 open reading frame 65 [ Homo sapiens (human) ]
• Official Symbol: C12orf65
• Synonyms: C12orf65; chromosome 12 open reading frame 65; CL065_HUMAN; COXPD7; mitochondrial; Probable peptide chain release factor C12orf65; probable peptide chain release factor C12orf65, mitochondrial; SPG55
• Gene ID: 91574
• mRNA Refseq: NM_001143905.2
• Protein Refseq: NP_001137377.1
• MIM: 613541
• UniProt ID: Q9H3J6
• Chromosome Location: 12q24.31
• Function: translation release factor activity