Recombinant Human BIK Protein, His-tagged

• Cat.No.: BIK-769H
• Product Overview: Recombinant Human BIK fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 17.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: BIK BCL2-interacting killer (apoptosis-inducing) [ Homo sapiens ]
• Official Symbol: BIK
• Synonyms: BIK; BCL2-interacting killer (apoptosis-inducing); bcl-2-interacting killer; NBK; apoptosis inducer NBK; apoptosis-inducing NBK; BP4; BIP1
• Gene ID: 638
• mRNA Refseq: NM_001197
• Protein Refseq: NP_001188
• MIM: 603392
• UniProt ID: Q13323