Recombinant Human BFSP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BFSP2-1494H
• Product Overview: BFSP2 MS Standard C13 and N15-labeled recombinant protein (NP_003562) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 45.9 kDa
• AA Sequence: MSERRVVVDLPTSASSSMPLQRRRASFRGPRSSSSLESPPASRTNAMSGLVRAPGVYVGTAPSGCIGGLGARVTRRALGISSVFLQGLRSSGLATVPAPGLERDHGAVEDLGGCLVEYMAKVHALEQVSQELETQLRMHLESKATRSGNWGALRASWASSCQQVGEAVLENARLMLQTETIQAGADDFKERYENEQPFRKAAEEEINSLYKVIDEANLTKMDLESQIESLKEELGSLSRNYEEDVKLLHKQLAGCELEQMDAPIGTGLDDILETIRIQWERDVEKNRVEAGALLQAKQQAEVAHMSQTQEEKLAAALRVELHNTSCQVQSLQAETESLRALKRGLENTLHDAKHWHDMELQNLGAVVGRLEAELREIRAEAEQQQQERAHLLARKCQLQKDVASYHALLDREESGTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BFSP2 beaded filament structural protein 2 [ Homo sapiens (human) ]
• Official Symbol: BFSP2
• Synonyms: BFSP2; beaded filament structural protein 2; CP47; CP49; LIFL-L; CTRCT12; PHAKOSIN
• Gene ID: 8419
• mRNA Refseq: NM_003571
• Protein Refseq: NP_003562
• MIM: 603212
• UniProt ID: Q13515