Bfsp2
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Official Full Name
beaded filament structural protein 2, phakinin -
Overview
Phakinin is a protein that in humans is encoded by the BFSP2 gene. More than 99% of the vertebrate ocular lens consists of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (CP49 or phakinin) and filensin (also known as CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. -
Synonyms
BFSP2;beaded filament structural protein 2, phakinin;CP47;CP49;LIFL-L;Phakinin;49 kDa cytoskeletal protein;beaded filament protein CP49;bfps2, Cytoskeletal protein, 49-kD;lens intermediate filament-like light;lens fiber cell beaded filament protein CP 47;lens fiber cell beaded filament protein CP 49;MGC142078;MGC142080;OTTHUMP00000216298;PHAKOSIN
Recombinant Proteins
- Zebrafish
- Mouse
- Chicken
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BFSP2-1922Z | Recombinant Zebrafish BFSP2 | Mammalian Cell | Zebrafish | His |
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| BFSP2-2389M | Recombinant Mouse BFSP2 Protein | Mammalian Cell | Mouse | His |
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| BFSP2-6771C | Recombinant Chicken BFSP2 | Mammalian Cell | Chicken | His |
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| BFSP2-8461HCL | Recombinant Human BFSP2 293 Cell Lysate | HEK293 | Human | Non |
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| BFSP2-1022M | Recombinant Mouse BFSP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| BFSP2-1022M-B | Recombinant Mouse BFSP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| BFSP2-1494H | Recombinant Human BFSP2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Bfsp2-351M | Recombinant Mouse Bfsp2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
Bfsp2 involved in several pathways and played different roles in them. We selected most pathways Bfsp2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Bfsp2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Bfsp2 has several biochemical functions, for example, protein binding,structural constituent of cytoskeleton,structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by Bfsp2 itself. We selected most functions Bfsp2 had, and list some proteins which have the same functions with Bfsp2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of eye lens | CRYGC,VIM,CRYBA4,CRYABB,CRYGD,ATXN1,CRYBB2,ASL1,CRYGB,CRYGS |
| protein binding | SUGT1,MSH2,USP20,LGALS6,MTIF3,GINS2,OAZ3,FANCI,UPK3A,GRIN2D |
| structural constituent of cytoskeleton | TUBB1,TUBA3C,ADD3,DES,ACTR2,TUBA8L2,KRT71,EPB41L3,CCDC6,TUBGCP4 |
Interacting Protein
Bfsp2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Bfsp2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Bfsp2.
SYCE1;ATF4;MBIP
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