Recombinant Human BECN1 Protein
Cat.No. : | BECN1-0745H |
Product Overview : | Recombinant Human BECN1 Protein without tag was expressed in E.coli. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis. Protects against infection by a neurovirulent strain of Sindbis virus. May play a role in antiviral host defense. |
Form : | Lyophilized powder/frozen liquid |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name | BECN1 beclin 1, autophagy related [ Homo sapiens (human) ] |
Official Symbol | BECN1 |
Synonyms | BECN1; beclin 1, autophagy related; beclin 1 (coiled coil, moesin like BCL2 interacting protein); beclin-1; ATG6; ATG6 autophagy related 6 homolog (S. cerevisiae); VPS30; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin1; |
Gene ID | 8678 |
mRNA Refseq | NM_003766 |
Protein Refseq | NP_003757 |
MIM | 604378 |
UniProt ID | Q14457 |
◆ Recombinant Proteins | ||
BECN1-10203H | Recombinant Human BECN1, GST-tagged | +Inquiry |
BECN1-295H | Recombinant Human BECN1 protein, His/MBP-tagged | +Inquiry |
BECN1-357R | Recombinant Rhesus Macaque BECN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BECN1-161HFL | Active Recombinant Full Length Human BECN1 Protein, C-Flag-tagged | +Inquiry |
BECN1-2778H | Recombinant Human BECN1 protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
BECN1-8470HCL | Recombinant Human BECN1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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