Recombinant Human BCL9 protein, His & T7-tagged

• Cat.No.: BCL9-1243H
• Product Overview: Recombinant Human BCL9 aa. (Ile1119~Gly1328 (Accession # O00512) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Ile1119~Gly1328
• Description: BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.4kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: BCL9 B-cell CLL/lymphoma 9 [ Homo sapiens (human) ]
• Official Symbol: BCL9
• Synonyms: BCL9; B-cell CLL/lymphoma 9; LGS; B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; protein legless homolog
• Gene ID: 607
• mRNA Refseq: NM_004326.3
• Protein Refseq: NP_004317.2
• UniProt ID: O00512