Recombinant Human BATF, His-tagged

• Cat.No.: BATF-3420H
• Product Overview: Recombinant human BATF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: BATF, also known as SFA2, is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. BATF is strongly expressed in mature T and B lymphocytes, and is up-regulated after transformation by human T-cell leukemia virus type I. BATF functions as a tissue-specific modulator of the AP-1 transcription complex in human cells. BATF also associates with IFP35, a leucine zipper protein that translocates to the nucleus following IFN treatment.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 40% glycerol.
• Molecular Weight: 16.2 kDa (145aa), confirmed by MALDI-TOF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by BCA assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QR R EKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFT SVL NSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BATF basic leucine zipper transcription factor, ATF-like [ Homo sapiens ]
• Synonyms: basic leucine zipper transcription factor, ATF-like; SFA2; B-ATF; BATF1; SFA-2; BATF;basic leucine zipper transcriptional factor ATF-like; SF-HT-activated gene 2 protein; activating transcription factor B; B-cell-activating transcription factor
• Gene ID: 10538
• mRNA Refseq: NM_006399
• Protein Refseq: NP_006390
• MIM: 612476
• UniProt ID: Q16520
• Chromosome Location: 14q24.3
• Function: RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity