BATF
-
Official Full Name
basic leucine zipper transcription factor, ATF-like -
Overview
Basic leucine zipper transcriptional factor ATF-like (BATF) is a basic leucine zipper (bZIP) transcription factor and is part of the AP-1/ATF family that forms inhibitory dimers with members of the Jun family (1-3). Expression of BATF is largely restricte -
Synonyms
BATF;basic leucine zipper transcription factor, ATF-like;basic leucine zipper transcriptional factor ATF-like;activating transcription factor B;B ATF;BATF1;SF HT activated gene 2;SFA 2;SF-HT-activated gene 2 protein;B-cell-activating transcription factor;SFA2;B-ATF;SFA-2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- Wheat Germ
- Mammalian Cell
- E.coli
- Mammalian cells
- In Vitro Cell Free System
- HEK293T
- HEK293
- GST
- His
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
BATF involved in several pathways and played different roles in them. We selected most pathways BATF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BATF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
BATF has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BATF itself. We selected most functions BATF had, and list some proteins which have the same functions with BATF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | NR5A2,KLF6,CLOCKB,PITX2,TCF7L1B,MYBL2,MESP1,ZFHX3,NKX6-1,NR2F5 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | NR3C1,CRX,TBX20,TXK,TFE3,MYC,HIF1A,MYBL2,NEUROD6,E2F4 |
| protein binding | PCBP1,ILVBL,ATRNL1,RBL1,FATE1,FSD2,DEAF1,APOOL,C3orf39,TDRD7 |
| sequence-specific DNA binding | MXTX2,FOXB1B,FOXP1,CREB5,FOXD1,HLX1,VDRB,DLX4B,EMX1,DLX2A |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | ZNF264,AKNA,GMEB1,RBPJA,KLF5,HSF1,FIGLA,IRF1,MEF2A,FOXJ2 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | ATF3,FOSL1A,RBPJB,ARNTL2,ARNTL,HIST2H3A,RBPJA,JDP2,BATF2,CLOCK |
Interacting Protein
BATF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BATF here. Most of them are supplied by our site. Hope this information will be useful for your research of BATF.
JUNB;DDIT3;GOPC;BACH1;JUN;JUND;CEBPB
Resources
Research Area
Natural Killer T (NKT) CellsB Cell Transcription Factors
T Follicular Helper (Tfh) Cells
Th17 Cells
Dendritic Cell Development
Related Services
Related Products
References
- Balabko, L; Andreev, K; et al. Increased expression of the Th17-IL-6R/pSTAT3/BATF/Ror gamma T-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung. SCIENTIFIC REPORTS 4:-(2014).
- Ubel, C; Sopel, N; et al. The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 133:198-+(2014).
