Recombinant Human BAFF soluble, FLAG-tagged

• Cat.No.: TNFSF13B-22H
• Product Overview: Produced in E. coli. The extracellular domain of human BAFF (aa 83-285) is fused at the N-terminus to a linker peptide (6 aa) and a FLAG tag.

Specification

• Species: Human
• Source: E.coli
• Tag: Flag
• Protein Length: 83-285 a.a.
• Form: Lyophilized. Contains PBS. Reconstitute with 100 μL of sterile water for 0.1 mg/mL solution. Further dilutions should be made with medium containing 5% fetal calf serum.
• Molecular Mass: ~28 kDa as determined by SDS-PAGE
• Endotoxin: Endotoxin:<0.1 eu/μg="" of="" purified="" protein="" (lal="">
• Purity: >95% as determined by SDS-PAGE.
• Applications: Mediates splenocyte survival. Detection of receptors of BAFF on target cells. Binds to human and mouse(weak) BCMA, TACI and BAFF-R.
• Usage: For in vitro research use only. Not for use in diagnostics or in humans.
• Storage: Store at -20°C. After reconstitution, prepare aliquots and store at -20°C.
• Warning: No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.

Gene Information

• Gene Name: TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b [ Homo sapiens ]
• Official Symbol: TNFSF13B
• Synonyms: TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; TNFSF20; tumor necrosis factor ligand superfamily member 13B; BAFF; BLYS; CD257; TALL 1; TALL1; THANK; delta BAFF; Delta4 BAFF; B-lymphocyte stimulator; B-cell-activating factor; ApoL related ligand TALL-1; TNF homolog that activates apoptosis; dendritic cell-derived TNF-like molecule; tumor necrosis factor-like protein ZTNF4; TNF and ApoL-related leukocyte expressed ligand 1; tumor necrosis factor (ligand) superfamily, member 20; DTL; ZTNF4; TALL-1
• Gene ID: 10673
• mRNA Refseq: NM_001145645
• Protein Refseq: NP_001139117
• MIM: 603969
• UniProt ID: Q9Y275
• Chromosome Location: 13q32-q34
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem
• Function: cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding