Recombinant Human ATG16L1 protein, His & GST-tagged

• Cat.No.: ATG16L1-1469H
• Product Overview: Recombinant Human ATG16L1 aa. (Met1~Gly284 (Accession # Q676U5)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Met1~Gly284
• Description: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 65.4kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6.9

Gene Information

• Gene Name: ATG16L1 autophagy related 16 like 1 [ Homo sapiens (human) ]
• Official Symbol: ATG16L1
• Synonyms: ATG16L1; autophagy related 16 like 1; IBD10; WDR30; APG16L; ATG16A; ATG16L; autophagy-related protein 16-1; APG16L beta; ATG16 autophagy related 16-like 1; WD repeat domain 30
• Gene ID: 55054
• mRNA Refseq: NM_001190266.1
• Protein Refseq: NP_001177195.1
• UniProt ID: Q676U5