Recombinant Human ASPN Protein, His-tagged

Specification
Gene Information
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Description :	This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 39.7 kDa Accurate Molecular Mass: 40 kDa
Protein length :	Phe57-Met371
Purity :	> 95%
Applications :	Positive Control; Immunogen; SDS-PAGE; WB.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer :	100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution :	Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Name	ASPN asporin [ Homo sapiens (human) ]
Official Symbol	ASPN
Synonyms	ASPN; asporin; asporin (LRR class 1); asporin proteoglycan; FLJ20129; PLAP1; SLRR1C; small leucine-rich protein 1C; periodontal ligament associated protein 1; OS3; PLAP-1
Gene ID	54829
mRNA Refseq	NM_001193335
Protein Refseq	NP_001180264
MIM	608135
UniProt ID	Q9BXN1