Recombinant Human ASNA1, His-tagged

• Cat.No.: ASNA1-9937H
• Product Overview: Recombinant Human ASNA1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-348a.a.
• Description: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) [ Homo sapiens ]
• Official Symbol: ASNA1
• Synonyms: ASNA1; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); arsA (bacterial) arsenite transporter, ATP binding, homolog 1; ATPase ASNA1; ARSA I; GET3; golgi to ER traffic 3 homolog (S. cerevisiae); transmembrane domain recognition complex; 40kDa; TRC40; arsenite-stimulated ATPase; arsenical pump-driving ATPase; golgi to ER traffic 3 homolog; transmembrane domain recognition complex, 40kDa; transmembrane domain recognition complex 40 kDa ATPase subunit; ARSA1; ARSA-I; ASNA-I; hASNA-I; MGC3821
• Gene ID: 439
• mRNA Refseq: NM_004317
• Protein Refseq: NP_004308
• MIM: 601913
• UniProt ID: O43681
• Chromosome Location: 19p13.13
• Function: ATP binding; ATPase activity; arsenite transmembrane transporter activity; hydrolase activity; metal ion binding; nucleotide binding; transporter activity