Recombinant Human ARSA, GST-tagged

Cat.No. : ARSA-9897H
Product Overview : Recombinant Human ARSA protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability March 15, 2025
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Species : Human
Source : E.coli
Tag : GST
Protein Length : 20-301a.a.
Description : The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name ARSA arylsulfatase A [ Homo sapiens ]
Official Symbol ARSA
Synonyms ARSA; arylsulfatase A; metachromatic leucodystrophy; ASA; cerebroside-sulfatase; MLD;
Gene ID 410
mRNA Refseq NM_000487
Protein Refseq NP_000478
MIM 607574
UniProt ID P15289
Chromosome Location 22q13.31-qter
Pathway Glycosphingolipid metabolism, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem;
Function arylsulfatase activity; calcium ion binding; cerebroside-sulfatase activity; hydrolase activity; sulfuric ester hydrolase activity;

Not For Human Consumption!

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