Recombinant Human ArsA Arsenite Transporter, ATP-binding, Homolog 1 (bacterial), His-tagged

• Cat.No.: ASNA1-7183H
• Product Overview: Recombinant human ASNA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 41.2kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-348aa
• Description: ASNA1, also as known as ARSA and TRC40, belongs to the arsA ATPase family. ASNA1 is the human homolog of the bacterial arsA gene. In E. coli, ArsA ATPase is the catalytic component of a multisubunit oxyanion pump that is responsible for resistance to arsenicals and antimonials. ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
• Molecular Mass: 41.2kDa (371aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAGVAG WGVEAEEFED APDVEPLEPT LSNIIEQRSL KWIFVGGKGG VGKTTCSCSL AVQLSKGRES VLIISTDPAH NISDAFDQKF SKVPTKVKGY DNLFAMEIDP SLGVAELPDE FFEEDNMLSM GKKMMQEAMS AFPGIDEAMS YAEVMRLVKG MNFSVVVFDT APTGHTLRLL NFPTIVERGL GRLMQIKNQI SPFISQMCNM LGLGDMNADQ LASKLEETLP VIRSVSEQFK DPEQTTFICV CIAEFLSLYE TERLIQELAK CKIDTHNIIV NQLVFPDPEK PCKMCEARHK IQAKYLDQME DLYEDFHIVK LPLLPHEVRG ADKVNTFSAL LLEPYKPPSA Q
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) [ Homo sapiens ]
• Official Symbol: ASNA1
• Synonyms: ASNA1; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); arsA (bacterial) arsenite transporter, ATP binding, homolog 1; ATPase ASNA1; ARSA I; GET3; golgi to ER traffic 3 homolog (S. cerevisiae); transmembrane domain recognition complex; 40kDa; TRC40; arsenite-stimulated ATPase; arsenical pump-driving ATPase; golgi to ER traffic 3 homolog; transmembrane domain recognition complex, 40kDa; transmembrane domain recognition complex 40 kDa ATPase subunit; ARSA1; ARSA-I; ASNA-I; hASNA-I; MGC3821
• Gene ID: 439
• mRNA Refseq: NM_004317
• Protein Refseq: NP_004308
• MIM: 601913
• UniProt ID: O43681
• Chromosome Location: 19p13.13
• Function: ATP binding; ATPase activity; arsenite transmembrane transporter activity; hydrolase activity; metal ion binding; nucleotide binding; transporter activity