Recombinant Human APPL2

• Cat.No.: APPL2-1002H
• Product Overview: Recombinant Human APPL2 was produced inInsect.

Specification

• Cat. No.: APPL2-1002H
• Description: APPL2, also termed as Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2, has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, APPL1, adiponectin receptors, and proteins of the NuRD/MeCP1 complex.
• Source: Insect.
• Amino Acid Sequence: GAMGSGIQRP MPAVDKLLLE EALQDSPQTR SLLSVFEEDA GTLTDYTNQL LQAMQRVYGA QNEMCLATQQ LSKQLLAYEK QNFALGKGDE EVISTLHYFS KVVDELNLLH TELAKQLADT MVLPIIQFRE KDLTEVSTLK DLFGLASNEH DLSMAKYSRL PKKKENEKVK TEVGKEVAAA RRKQHLSSLQ YYCALNALQY RKQMAMMEPM IGFAHGQINF FKKGAEMFSK RMDSFLSSVA DMVQSIQVEL EAEAEKMRVS QQELLSVDES VYTPDSDVAA PQINRNLIQK AGYLNLRNKT GLVTTTWERL YFFTQGGNLM CQPRGAVAGG LIQDLDNCSV MAVDCEDRRY CFQITTPNGK SGIILQAESR KENEEWICAI NNISRQIYLT DNPEAVAIKL NQTALQAVTP ITSFGKKQES SCPSQNLKNS EMENENDKIV PKATASLPEA EELIAPGTPI QFDIVLPATE FLDQNRGSRR TNPFGETEDE SFPEAEDSLL QQMFIVRFLG SMAVKTDSTT EVIYEAMRQV LAARAIHNIF RMTESHLMVT SQSLRLIDPQ TQVSRANFEL TSVTQFAAHQ ENKRLVGFVI RVPESTGEES LSTYIFESNS EGEKICYAIN LGKEIIEVQK DPEALAQLML SIPLTNDGKY VLLNDQPDDD DGNPNEHRGA ESEA
• Form: Filtered (0.22 μm) and lyophilized in 1 mg/mL in PBS.
• Purity: >98%.
• Applications: ELISA, Western blotting, Immunoprecipitation.
• Quality Control Test: BCA to determine quantity of the protein. SDS PAGE to determine purity of the protein.
• Reconstitution: Add deionized water to prepare a working stock solution of approximately 1 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
• Storage: Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
• Tag: Non

Gene Information

• Gene Name: APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 [ Homo sapiens ]
• Synonyms: APPL2; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DIP13B; FLJ10659; DIP13 beta; adaptor protein containing PH domain, PTB domain and leucine zipper motif 2; DCC-interacting protein 13-beta; Dip13-beta; Dip13-beta; leucine zipper motif 2
• Gene ID: 55198
• mRNA Refseq: NM_018171
• Protein Refseq: NP_060641
• MIM: 606231
• UniProt ID: Q8NEU8
• Chromosome Location: 12q24.1
• Function: protein binding