Recombinant Human APOC1 Protein, His&GST-tagged

• Cat.No.: APOC1-220H
• Product Overview: Recombinant Human APOC1 Protein (Thr27-Ser83) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 36.6 kDa
  Accurate Molecular Mass: 40 kDa
• Protein length: Thr27-Ser83
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: APOC1 apolipoprotein C-I [ Homo sapiens (human) ]
• Official Symbol: APOC1
• Synonyms: APOC1; apolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1
• Gene ID: 341
• mRNA Refseq: NM_001645
• Protein Refseq: NP_001636
• MIM: 107710
• UniProt ID: P02654