Recombinant Human API5 Protein, MYC/DDK-tagged

• Cat.No.: API5-2310H
• Product Overview: Recombinant human API5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 50.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: API5 apoptosis inhibitor 5 [ Homo sapiens ]
• Official Symbol: API5
• Synonyms: AAC-11; AAC11
• Gene ID: 8539
• mRNA Refseq: NM_001142930
• Protein Refseq: NP_001136402
• MIM: 609774
• UniProt ID: Q9BZZ5