Recombinant Human ANXA5 Protein, His-tagged

• Cat.No.: ANXA5-001H
• Product Overview: Recombinant Human ANXA5 Protein 1-320 aa (full-length) with a 6xHis tag was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-320 a.a.
• Description: The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications.
• Molecular Mass: 39 kDa
• Purity: >95% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB).
• Applications: ELISA, WB, Antibody Production, Protein array
• Quality Control Test: 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB) serum and peptide fingerprinting by MALDI-TOF-TOF mass spectrometry.
• Storage: Store working aliquots at 4 centigrade for up to one week.
  For extended storage, conserve at −80 centigrade.
• Expiry: 12 months from the date of purchase, if it is properly stored.
• Storage Buffer: 20mM Tris-HCl, 0.5M NaCl, 100mM imidazole, 1mM 2-mercaptoethanol, pH:8.0. No preservatives added.
• Shipping: Dry Ice

Gene Information

• Gene Name: ANXA5 annexin A5 [ Homo sapiens (human) ]
• Official Symbol: ANXA5
• Synonyms: ANXA5; annexin A5; PP4; ANX5; ENX2; RPRGL3; HEL-S-7; annexin A5; CBP-I; PAP-I; VAC-alpha; anchorin CII; annexin V; annexin-5; calphobindin I; endonexin II; epididymis secretory protein Li 7; lipocortin V; placental anticoagulant protein 4; placental anticoagulant protein I; thromboplastin inhibitor; vascular anticoagulant-alpha
• Gene ID: 308
• mRNA Refseq: NM_001154
• Protein Refseq: NP_001145
• MIM: 131230
• UniProt ID: P08758