Recombinant Human ANO6, GST-tagged

• Cat.No.: ANO6-9683H
• Product Overview: Recombinant Human ANO6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-294a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ANO6 anoctamin 6 [ Homo sapiens ]
• Official Symbol: ANO6
• Synonyms: ANO6; anoctamin 6; TMEM16F, transmembrane protein 16F; anoctamin-6; DKFZp313M0720; transmembrane protein 16F; SCTS; BDPLT7; TMEM16F; MGC104751
• Gene ID: 196527
• mRNA Refseq: NM_001025356
• Protein Refseq: NP_001020527
• MIM: 608663
• UniProt ID: Q4KMQ2
• Chromosome Location: 12q12-q13.11
• Function: chloride channel activity; ion channel activity