Recombinant Human angiogenin, ribonuclease, RNase A family, 5, His-tagged

• Cat.No.: ANG-507H
• Product Overview: ANG, 25-147aa Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 25-147 a.a.
• Description: ANG, as known as Angiogenin, belongs to RNase A family. This protein is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Recombinant human ANG protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 16.4 kDa(144aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MQDNSRYTHF LTQHYDAKPQ GRDDRYCESI MRRRGLTSPC KDINTFIHGN KRSIKAICEN KNGNPHRENL RISKSSFQVT TCKLHGGSPW PPCQYRATAG FRNVVVACEN GLPVHLDQSI FRRP
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ANG angiogenin, ribonuclease, RNase A family, 5 [ Homo sapiens ]
• Official Symbol: ANG
• Synonyms: ANG; angiogenin, ribonuclease, RNase A family, 5; angiogenin; RNASE5; RNase 5; ribonuclease 5; epididymis luminal protein 168; ALS9; HEL168; RNASE4; MGC22466; MGC71966
• Gene ID: 283
• mRNA Refseq: NM_001097577
• Protein Refseq: NP_001091046
• MIM: 105850
• UniProt ID: P03950
• Chromosome Location: 14q11.1-q11.2
• Function: DNA binding; actin binding; copper ion binding; endonuclease activity; heparin binding; hydrolase activity; pancreatic ribonuclease activity; peptide binding; protein binding; rRNA binding; receptor binding; ribonuclease activity