Recombinant Human ALG1, GST-tagged

• Cat.No.: ALG1-9569H
• Product Overview: Recombinant Human ALG1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-308a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ALG1 asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ALG1
• Synonyms: ALG1; asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 1 homolog (yeast, beta 1,4 mannosyltransferase); chitobiosyldiphosphodolichol beta-mannosyltransferase; HMAT1; HMT 1; mannosyltransferase-1; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); HMT1; MT-1; CDG1K; HMT-1; Mat-1; hMat-1
• Gene ID: 56052
• mRNA Refseq: NM_019109
• Protein Refseq: NP_061982
• MIM: 605907
• UniProt ID: Q9BT22
• Chromosome Location: 16p13.3
• Pathway: Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; N-glycan precursor biosynthesis, organism-specific biosystem
• Function: chitobiosyldiphosphodolichol beta-mannosyltransferase activity; mannosyltransferase activity; transferase activity, transferring glycosyl groups