ALG1
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Official Full Name
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) -
Overview
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik. -
Synonyms
ALG1;asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae);asparagine linked glycosylation 1 homolog (yeast, beta 1,4 mannosyltransferase);chitobiosyldiphosphodolichol beta-mannosyltransferase;HMAT1;HMT 1;4-mannosyltransferase;ALG1_HUMAN;asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase);Asparagine-linked glycosylation protein 1 homolog;Beta 1 4 mannosyltransferase;Beta-1;CDG1K;GDP Man GlcNAc2 PP dolichol mannosyltransferase;GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase;GDP-mannose-dolichol diphosphochitobiose mannosyltransferase;Hmat-1;HMT1;Mannosyltransferase 1;Mannosyltransferase-1;MT 1;MT-1;MT1;OTTHUMP00000159923;beta-1,4 mannosyltransferase;beta-1,4-mannosyltransferase;HMT-1;Mat-1
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- S.cerevisiae
- Schizosaccharomyces pombe
- Yarrowia lipolytica
- Debaryomyces hansenii
- Dictyostelium Discoideum
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E. coli
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- GST
- His
- Non
- N-His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ALG1 involved in several pathways and played different roles in them. We selected most pathways ALG1 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolic pathways | ADSL,NDUFA9A,PFKMB,ZNRD1,UCK2A,GALC,SGSH,PIGL,PLD2,SORD |
N-Glycan biosynthesis | ALG5,ALG14,MGAT2,ST6GAL2,DOLPP1,MGAT4C,MAN1C1,ST6GAL2A,MGAT4A,DPAGT1 |
Protein Function
ALG1 has several biochemical functions, for example, chitobiosyldiphosphodolichol beta-mannosyltransferase activity,mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG1 itself. We selected most functions ALG1 had, and list some proteins which have the same functions with ALG1. You can find most of the proteins on our site.
Function | Related Protein |
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mannosyltransferase activity | GTDC2,ZNF408,ALG12,POMT1,GALNTL4,4931440L10Rik,PIGZ,PIGV,DPY19L1,B3GNTL1 |
Interacting Protein
ALG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG1.
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