Recombinant Human Aldehyde Dehydrogenase 1 Family, Member B1, GST-tagged

• Cat.No.: ALDH1B1-488H
• Product Overview: Recombinant Human ALDH1B1protein was expressed as gst-tagged fusion protein by E. coli and purified byGSH-sepharose. The purified protein was resolved in 1M PBS (58mM Na2HPO4,17mMNaH2PO4, 68mM NaCl, pH8.) added with 100mM GSH and 1% TritonX-100,15%glycerol.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: ALDH1B1 belongs tothe aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is thesecond enzyme of the major oxidative pathway of alcohol metabolism. ALDH1B1does not contain introns in the coding sequence. The variation of this locusmay affect the development of alcohol-related problems.
• Antigen peptideregion: 168-517aa
• Full length: False
• Storage: Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.

Gene Information

• Gene Name: ALDH1B1 aldehyde dehydrogenase 1family, member B1 [ Homo sapiens ]
• Official Symbol: ALDH1B1
• Synonyms: ALDH1B1;aldehyde dehydrogenase 1 family, member B1; ALDH5; ALDHX; aldehydedehydrogenase X, mitochondrial; ALDH class 2; aldehyde dehydrogenase 5;acetaldehyde dehydrogenase 5; MGC2230; EC 1.2.1.3; EC 1.2.1;OTTHUMP00000021399
• Gene ID: 219
• mRNA Refseq: NM_000692
• Protein Refseq: NP_000683
• MIM: 100670
• UniProt ID: P30837
• Chromosome Location: 9p11.1
• Pathway: Arginine and prolinemetabolism; Ascorbate and aldarate metabolism; Fatty acid metabolism; GABAbiosynthesis; Glycerolipid metabolism; Glycolysis / Gluconeogenesis;Histidine metabolism; Lysine degradation; Metabolic pathways; Pentose andglucuronate interconversions; Propanoate metabolism; Pyruvate metabolism;Tryptophan metabolism; Valine; beta-Alanine metabolism
• Function: aldehydedehydrogenase (NAD) activity; oxidoreductase activity