ALDH1B1
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Official Full Name
aldehyde dehydrogenase 1 family, member B1 -
Overview
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. -
Synonyms
ALDH1B1;aldehyde dehydrogenase 1 family, member B1;ALDH5;aldehyde dehydrogenase X, mitochondrial;ALDHX;Aldehyde dehydrogenase 5;mitochondrial;Acetaldehyde dehydrogenase 5;AL1B1_HUMAN;Aldehyde dehydrogenase 1B1;Aldehyde dehydrogenase family 1 member B1;Aldehyde dehydrogenase X;Aldehyde dehydrogenase X mitochondrial;ALDH class 2;MGC2230;Mitochondrial aldehyde dehydrogenase X;OTTHUMP00000021399
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- E. coli
- Mammalian cells
- In Vitro Cell Free System
- HEK293T
- His
- GST
- Non
- N-GST
- Flag
- Myc&DDK
- His&Fc&Avi
- N-His-GST&C-V5-Myc
Involved Pathway
ALDH1B1 involved in several pathways and played different roles in them. We selected most pathways ALDH1B1 participated on our site, such as Glycolysis / Gluconeogenesis,Pentose and glucuronate interconversions,Ascorbate and aldarate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH1B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid degradation | ADH1C,PECI,ADH7,ACOX1,CPT2,HADHAA,EHHADH,CPT1C,ECI1,GCDHA |
| Tryptophan metabolism | AOX1,AOX2P,OGDHA,AOC1,RNF25,TDO2B,OGDHL,ASMT,ALDH3A2,ALDH2 |
| Metabolic pathways | OXSR1,HADHB,MTMR7,NMNAT2,HPSE,PKM,ATP5O,ASAH1,CDIPT,PDHA1B |
| Glycolysis / Gluconeogenesis | HKDC1,PGM2,G6PC3,GALM,LDHB,DLDH,PDHB,MINPP1,PGK1,AKR1A1 |
| Histidine metabolism | ALDH3A2,AMDHD1,CNDP2,ALDH3A2A,AOC1,FTCD,HDC,ALDH2,CNDP1,ALDH9A1B |
| Glycerolipid metabolism | MOGAT3A,MBOAT2B,AGK,DGKZ,DAK,GK,AKR1B7,AKR1A1A,AGPAT9L,MOGAT2 |
| Arginine and proline metabolism | NOS2B,SMS,MAOA,DHDPSL,SRM,AOC1,ADC,HOGA1,NOS1,AGMAT |
| Pentose and glucuronate interconversions | UGT2B7,UGT1AB,UGP2B,GKUP,AKR1B8,DHDH,UGT1A7C,OXSR1,DHDHL,CRYL1 |
| Valine, leucine and isoleucine degradation | ACAT1,BCKDHB,AOX1,ACAT2,ALDH7A1,HIBADHB,IVD,ACSF3,AUH,MCEE |
Protein Function
ALDH1B1 has several biochemical functions, for example, aldehyde dehydrogenase (NAD) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH1B1 itself. We selected most functions ALDH1B1 had, and list some proteins which have the same functions with ALDH1B1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aldehyde dehydrogenase (NAD) activity | ALDH16A1,ALDH4A1,Aldh1a7,ALDH5A1,ALDH3B2,ALDH9A1B,ALDH3A2B,ALDH1L2,ALDH2,ALDH7A1 |
Interacting Protein
ALDH1B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH1B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH1B1.
FABP2;Bub1;MYC;FN1;Tubg1;Lgals3bp;HDAC1;ICT1;LLGL1;SGOL1;ATL3;Bag2;MAP1LC3B;MAP1LC3A
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