Recombinant Human ALAS2 Protein, His-tagged

• Cat.No.: ALAS2-112H
• Product Overview: Recombinant Human ALAS2 Protein (Ala361-Ala587) with N-His tag was expressed in E. coli.

Specification

• Description: The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.6 kDa
  Accurate Molecular Mass: 29 kDa
• Protein length: Ala361-Ala587
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: ALAS2 aminolevulinate, delta-, synthase 2 [ Homo sapiens (human) ]
• Official Symbol: ALAS2
• Synonyms: ALAS2; aminolevulinate, delta-, synthase 2; aminolevulinate, delta, synthase 2 (sideroblastic/hypochromic anemia), ASB; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; sideroblastic/hypochromic anemia; delta-ALA synthase 2; delta-ALA synthetase; 5-aminolevulinic acid synthase 2; delta-aminolevulinate synthase 2; ASB; ANH1; XLSA; ALASE; XLDPP; XLEPP; ALAS-E; FLJ93603
• Gene ID: 212
• mRNA Refseq: NM_000032
• Protein Refseq: NP_000023
• MIM: 301300
• UniProt ID: P22557