Recombinant Human AKAP11 Protein, His-tagged

• Cat.No.: AKAP11-395H
• Product Overview: Recombinant Human AKAP11(Leu1650~Ala1901) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 31.4kDa
• Protein length: Leu1650~Ala1901
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: AKAP11 A-kinase anchoring protein 11 [ Homo sapiens ]
• Official Symbol: AKAP11
• Synonyms: PRKA11; AKAP-11; AKAP220; PPP1R44; A kinase (PRKA) anchor protein 11; A-kinase anchor protein 220 kDa
• Gene ID: 11215
• mRNA Refseq: NM_016248
• Protein Refseq: NP_057332
• UniProt ID: Q9UKA4