Recombinant Human AIP, His-tagged

• Cat.No.: AIP-4960H
• Product Overview: Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-330aa
• Description: The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
• Molecular Mass: 39.8 kDa (350aa), confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: AIP aryl hydrocarbon receptor interacting protein [ Homo sapiens ]
• Official Symbol: AIP
• Synonyms: AIP; ARA9; XAP2; FKBP16; FKBP37; SMTPHN; aryl hydrocarbon receptor interacting protein; XAP-2; AH receptor-interacting protein; OTTHUMP00000236411; OTTHUMP00000236412; HBV-X associated protein; immunophilin homolog ARA9; HBV X-associated protein 2; aryl hydrocarbon receptor-interacting protein; aryl-hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; Aryl-hydrocarbon receptor-interacting protein; Immunophilin homolog ARA9
• Gene ID: 9049
• mRNA Refseq: NM_003977
• Protein Refseq: NP_003968
• MIM: 605555
• UniProt ID: O00170
• Chromosome Location: 11q13.3
• Pathway: AhR pathway
• Function: protein binding; signal transducer activity; transcription coactivator activity; transcription factor binding; unfolded protein binding