AIP
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Official Full Name
aryl hydrocarbon receptor interacting protein -
Overview
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The;encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported;to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded;protein can bind specifically to and inhibit the activity of hepatitis B virus. -
Synonyms
AIP;aryl hydrocarbon receptor interacting protein;AH receptor-interacting protein;AH receptor interacting protein;AIP_HUMAN;ARA 9;Aryl-hydrocarbon receptor-interacting protein;fa03h10;FKBP 16;FKBP 37;FKBP16;FKBP37;HBV X associated protein 2;HBV X associated protein;HBV X-associated protein 2;HBVX associated protein;Immunophilin homolog ARA 9;Immunophilin homolog ARA9;SMTPHN;XAP 2;XAP-2;XAP2
Recombinant Proteins
- Zebrafish
- Mouse
- Rhesus macaque
- Human
- Rat
- Chicken
- Mammalian Cells
- E.Coli/Yeast
- E.coli
- Wheat Germ
- HEK293
- His
- GST
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
AIP involved in several pathways and played different roles in them. We selected most pathways AIP participated on our site, such as AhR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| AhR pathway | CDKN1B,NQO1,PTGES3,EGFR,CYP1B1,JUND,CDKN1A,CDC37,JUN,AHRR |
Protein Function
AIP has several biochemical functions, for example, GAF domain binding,aryl hydrocarbon receptor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AIP itself. We selected most functions AIP had, and list some proteins which have the same functions with AIP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | GTF2A1,ATXN7L3,NR1I2,PER2,TFAP2A,BRCA1,VGLL1,NFYC,ING4,RIPK3 |
| aryl hydrocarbon receptor binding | ARNT2,ARNTL,ARNT |
| unfolded protein binding | DNAJB6,DNAJA3B,CHAF1A,APCS,ST13,TUBB4B,CCT3,CLPX,HSPA6,HSP90AA1.1 |
| protein binding | EIF2B1,FAM19A1,PTGFRN,FAP,QRICH1,SCRN2,GNAQ,MPZL1L,COBL,RANBP3 |
| transcription factor binding | JUNB,CDKN2A,TFDP1A,LEF1,HAND1,NBN,ESRRB,PURA,CAMTA2,NAB2 |
| signal transducer activity | PLCD1B,CXCR4B,GNA12A,OLFR186,PLCXD2,CCR1L1,OLFCJ1,OPN1LW1,MAGI2,TAAR12C |
Interacting Protein
AIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AIP here. Most of them are supplied by our site. Hope this information will be useful for your research of AIP.
PDE2A;HSP90AB1;IRF7;AHR;CSNK2A1;URI1;EBNA3;MAX;SIM2;q308m6_human
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References
- Chieh, JJ; Huang, KW; et al. Sub-tesla-field magnetization of vibrated magnetic nanoreagents for screening tumor markers. APPLIED PHYSICS LETTERS 106:-(2015).
- Dudani, JS; Gossett, DR; et al. Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles. BIOMICROFLUIDICS 9:-(2015).
