Recombinant Human AIMP1, His-tagged

• Cat.No.: AIMP1-940H
• Product Overview: Recombinant human AIMP1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 39.2 kDa (356aa).

Specification

• Cat. No.: AIMP1-940H
• Description: AIMP1, also known as EMPA2 or p43, is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 2mM DTT, 10% glycerol.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MLPAVAVSEP VVLRFMIFCR LLAKMANNDA VLKRLEQKGA EADQIIEYLK QQVSLLKEKA ILQATLREEK KLRVENAKLK KEIEELKQEL IQAEIQNGVK QIPFPSGTPL HANSMVSENV IQSTAVTTVS SGTKEQIKGG TGDEKKAKEK IEKKGEKKEK KQQSIAGSAD SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 [ Homo sapiens ]
• Synonyms: SCYE1; AIMP1; EMAP II; EMAP-2; EMAP-II; EMAP2; EMAPII; p43; small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating); small inducible cytokine subfamily E, member 1; OTTHUMP00000161878; ARS-interacting multifunctional protein 1; endothelial monocyte-activating polypeptide 2; endothelial-monocyte activating polypeptide II; multisynthetase complex auxiliary component p43
• Gene ID: 9255
• mRNA Refseq: NM_001142415
• Protein Refseq: NP_001135887
• MIM: 603605
• UniProt ID: Q12904
• Chromosome Location: 4q2
• Function: cell surface binding; cytokine activity; protein binding; protein homodimerization activity; tRNA binding