Recombinant Human AFF3, His-tagged

• Cat.No.: AFF3-3232H
• Product Overview: AF4/FMR2 family member 3 (AFF3), partial

Specification

• Description: This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 1251
• Purity: >90%
• Notes: Small volumes of AFF3 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AFF3 AF4/FMR2 family, member 3 [ Homo sapiens ]
• Official Symbol: AFF3
• Synonyms: AFF3; AF4/FMR2 family, member 3; LAF4, lymphoid nuclear protein related to AF4; AF4/FMR2 family member 3; MLLT2 like; protein LAF-4; MLLT2-related protein; lymphoid nuclear protein 4; lymphoid nuclear protein related to AF4; LAF4; MLLT2-like
• Gene ID: 3899
• mRNA Refseq: NM_001025108
• Protein Refseq: NP_001020279
• MIM: 601464
• UniProt ID: P51826
• Chromosome Location: 2q11.2-q12
• Function: DNA binding; double-stranded DNA binding