Recombinant Human Adrenergic, Beta, Receptor Kinase 2, GST-tagged

• Cat.No.: ADRBK2-1179H
• Product Overview: Recombinant humanADRBK2 is a serine/threonine kinase that is thought to act as a regulator ofreceptor function.

Specification

• Cat. No.: ADRBK2-1179H
• Description: ADRBK2(beta-ARK-2) also known as G-protein-coupled receptor kinase 3 (GRK3) is anenzyme that in humans is encoded by the ADRBK2 gene. The ADRBK2 specifically phosphorylates the agonist-occupiedform of the beta-adrenergic and related G protein-coupled receptors.
• Source: Insect cells
• Species: Human
• Form: Liquid in 50 mMTris-HCl, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02%. Triton X-100 + 2 mM DTT+ 50% glycerol.
• Molecular Weight: 107.2 kDa
• Concentration: 0.44 mg/ml
• Purity: > 90% asdetermined by SDS-PAGE analysis.
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: ADRBK2

Gene Information

• Gene Name: ADRBK2 adrenergic, beta, receptorkinase 2 [ Homo sapiens ]
• Synonyms: ADRBK2; adrenergic,beta, receptor kinase 2; GRK3; BARK2; beta-adrenergic receptor kinase 2;beta-ARK-2; OTTHUMP00000196857; G-protein-coupled receptor kinase 3;Beta-ARK-2; EC 2.7.11; EC 2.7.11.15
• Gene ID: 157
• mRNA Refseq: NM_005160
• Protein Refseq: NP_005151
• MIM: 109636
• UniProt ID: P35626
• Chromosome Location: 22q11; 22q12.1
• Pathway: Chemokine signalingpathway; Endocytosis; Glutamatergic synapse; IL-4 signaling Pathway;Olfactory transduction; Thromboxane A2 receptor signaling
• Function: ATP binding;G-protein coupled receptor kinase activity; beta-adrenergic receptor kinaseactivity; nucleotide binding; protein kinase activity; signal transduceractivity; transferase activity, transferring phosphorus-containing groups