Recombinant Human ADP-Ribosylation Factor 4, His-tagged

• Cat.No.: ARF4-3396H
• Product Overview: Recombinant human ARF4 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.0 kDa (204aa).

Specification

• Cat. No.: ARF4-3396H
• Description: ARF4 is a member of the ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The ARF proteins include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. They are categorized as class I, class II and class III; this gene is a class II member.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M Nacl, 5mM DTT, 20% glycerol.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSHMGLTIS SLFSRLFGKK QMRILMVGLD AAGKTTILYK LKLGEIVTTI PTIGFNVETV EYKNICFTVW DVGGQDRIRP LWKHYFQNTQ GLIFVVDSND RERIQEVADE LQKMLLVDEL RDAVLLLFAN KQDLPNAMAI SEMTDKLGLQ SLRNRTWYVQ ATCATQGTGL YEGLDWLSNE LSKR.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ARF4 ADP-ribosylation factor 4 [ Homo sapiens ]
• Synonyms: ADP-ribosylation factor 4;ARF2; ARF4; ADP-ribosylation factor 4; OTTHUMP00000213142; OTTHUMP00000213211; ADP-ribosylation factor 2
• Gene ID: 378
• mRNA Refseq: NM_001660
• Protein Refseq: NP_001651
• MIM: 601177
• UniProt ID: P18085
• Chromosome Location: 3p21.2-p21.1
• Function: GTP binding; GTPase activity; epidermal growth factor receptor binding; nucleotide binding