Recombinant Human ARF4, GST-tagged

• Cat.No.: ARF4-9801H
• Product Overview: Recombinant Human ARF4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-180a.a.
• Description: This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARF4 ADP-ribosylation factor 4 [ Homo sapiens ]
• Official Symbol: ARF4
• Synonyms: ARF4; ADP-ribosylation factor 4; ADP ribosylation factor 2 , ARF2; ADP-ribosylation factor 2; ARF2
• Gene ID: 378
• mRNA Refseq: NM_001660
• Protein Refseq: NP_001651
• MIM: 601177
• UniProt ID: P18085
• Chromosome Location: 3p21.2-p21.1
• Pathway: EGFR1 Signaling Pathway, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding