Recombinant Human ADCYAP1 protein, His & GST-tagged

• Cat.No.: ADCYAP1-6840H
• Product Overview: Recombinant Human ADCYAP1 aa. (Ile17~Leu176 (Accession # P18509)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 47.2kDa.
• Protein length: Ile17~Leu176
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ADCYAP1 adenylate cyclase activating polypeptide 1 [ Homo sapiens (human) ]
• Official Symbol: ADCYAP1
• Synonyms: PACAP; adenylate cyclase activating polypeptide 1 (pituitary); prepro-PACAP; pituitary adenylate cyclase-activating polypeptide
• Gene ID: 116
• mRNA Refseq: NM_001099733.1
• Protein Refseq: NP_001093203.1
• UniProt ID: P18509