Recombinant Human ADARB1 cell lysate

• Cat.No.: ADARB1-28HCL

Specification

• Description: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: ADARB1 adenosine deaminase, RNA-specific, B1 [ Homo sapiens ]
• Official Symbol: ADARB1
• Synonyms: ADARB1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA specific, B1 (homolog of rat RED1); double-stranded RNA-specific editase 1; ADAR2; ADAR2a; ADAR2a L1; ADAR2a L2; ADAR2a L3; ADAR2b; ADAR2c; ADAR2d; ADAR2g; DRABA2; DRADA2; hRED1; RED1; RED1 homolog (rat); RNA editase; RED1 homolog; RNA-editing enzyme 1; RNA editing deaminase 1; RNA-editing deaminase 1; dsRNA adenosine deaminase; human dsRNA adenosine deaminase DRADA2; adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); adenosine deaminase, RNA-specific, B1 (homolog of rat RED1)
• Gene ID: 104
• mRNA Refseq: NM_001112
• Protein Refseq: NP_001103
• MIM: 601218
• UniProt ID: P78563
• Chromosome Location: 21q22.3
• Pathway: C6 deamination of adenosine, organism-specific biosystem; Formation of editosomes by ADAR proteins, organism-specific biosystem; Gene Expression, organism-specific biosystem; mRNA Editing, organism-specific biosystem; mRNA Editing: A to I Conversion, organism-specific biosystem
• Function: RNA binding; adenosine deaminase activity; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; double-stranded RNA binding; hydrolase activity; mRNA binding; metal ion binding