Recombinant Human ADAMTS12 protein, His-tagged

• Cat.No.: ADAMTS12-1485H
• Product Overview: Recombinant Human ADAMTS12 aa. (Gln823~Pro997 (Accession # P58397)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.1kDa
• Protein length: Gln823~Pro997
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.5

Gene Information

• Gene Name: ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 [ Homo sapiens (human) ]
• Official Symbol: ADAMTS12
• Synonyms: ADAMTS12; ADAM metallopeptidase with thrombospondin type 1 motif 12; PRO4389; A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS 12; ADAM-TS12; ADAMTS-12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12
• Gene ID: 81792
• mRNA Refseq: NM_001324511.1
• Protein Refseq: NP_001311440.1
• UniProt ID: P58397