Recombinant Human ADAM9, His-tagged

• Cat.No.: ADAM9-3005H
• Product Overview: A Disintegrin And Metalloprotease 9 (ADAM9)

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 819
• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
• Form: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Molecular Mass: 27.3kDa
• Endotoxin: <1.0eu per 1ug (determined by the lal</1.0eu
• Purity: >95%
• Applications: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Notes: Small volumes of ADAM9 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ADAM9 ADAM metallopeptidase domain 9 [ Homo sapiens ]
• Official Symbol: ADAM9
• Synonyms: ADAM9; ADAM metallopeptidase domain 9; a disintegrin and metalloproteinase domain 9 (meltrin gamma) , cone rod dystrophy 9 , CORD9; disintegrin and metalloproteinase domain-containing protein 9; KIAA0021; MCMP; MDC9; meltrin gamma; Mltng; cone rod dystrophy 9; myeloma cell metalloproteinase; cellular disintegrin-related protein; ADAM metallopeptidase domain 9 (meltrin gamma); metalloprotease/disintegrin/cysteine-rich protein 9; CORD9
• Gene ID: 8754
• mRNA Refseq: NM_003816
• Protein Refseq: NP_003807
• MIM: 602713
• UniProt ID: Q13443
• Chromosome Location: 8p11.23
• Function: SH3 domain binding; SH3 domain binding; collagen binding; integrin binding; integrin binding; integrin binding; laminin binding; metal ion binding; metalloendopeptidase activity; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; protein binding; protein kinase C binding; zinc ion binding