Recombinant Human ADAM8 protein, His & T7-tagged

• Cat.No.: ADAM8-615H
• Product Overview: Recombinant Human ADAM8 aa. (Ser371~Glu587 (Accession # P78325)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Ser371~Glu587
• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.2kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.2.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ADAM8 ADAM metallopeptidase domain 8 [ Homo sapiens (human) ]
• Official Symbol: ADAM8
• Synonyms: ADAM8; ADAM metallopeptidase domain 8; MS2; CD156; CD156a; disintegrin and metalloproteinase domain-containing protein 8; a disintegrin and metalloproteinase domain 8; cell surface antigen MS2; human leukocyte differentiation antigen
• Gene ID: 101
• mRNA Refseq: NM_001109.4
• Protein Refseq: NP_001100.3
• UniProt ID: P78325